3. Hemoperfusion
Hemoperfusion
Advanced blood purification therapy for removing toxins and inflammatory mediators. Hemoperfusion uses whole blood (not plasma like in DFPP) and an adsorption cartridge.
What is hemoperfusion?
Hemoperfusion (HP) is a medical treatment that involves passing the patient's blood through a device containing an adsorbent material that removes toxic substances.
Because this is a selective method and the patient loses only a small volume of blood in the filter, no donor plasma is required.
What Hemoperfusion Removes
- Pro- and anti-inflammatory mediators
- Apo-B lipoproteins [e.g. LDL, Lp(a)]
- β-2 Microglobulin
- High levels of cytokines
- Elevated bilirubin
- Myoglobin
Treatment Applications
- Sepsis / Severe Sepsis / Septic Shock
- Multiple Organ Failure Syndrome (MOF)
- Familial Hypercholesterolemia
- Dialysis-Related Amyloidosis (DRA)
- Lp(a) Hyperlipoproteinemia
- Systemic Inflammatory Response Syndrome (SIRS)
- Treatment of rhabdomyolysis
- Hyperbilirubinemia
- In Germany used as a support therapy for patients undergoing chemotherapy (hemoperfusion does not treat cancer, it only eases the side effects of chemotherapy)

Benefits of Hemoperfusion
- Targeted removal: Selectively eliminates specific toxins and inflammatory mediators
- Rapid action: Provides quick reduction of harmful substances in critical conditions
- Complementary therapy: Can be used alongside other treatments for enhanced results
- Customizable approach: Treatment parameters (the filter) can be adjusted based on patient needs
- Broad application: Effective for multiple medical conditions across different specialties